報告題目：An algorithm based on integrated dynamical systems for an artificial pancreas (一種基於集成動力系統的人工胰腺算法)
報告人：李嘉旭,副教授（University of Louisville）.博士生導師。曾在美國高科技工業領域工作十余年，歷任程序分析員、工程師、資深工程師、高級工程師、資深高級工程師。期間主要從事局部半導體工藝流程中的研發工作，包括實時控製的設計開發、矽晶研磨系統的閉環控製的研究和開發，定義了多個CPU小系統之間的通訊協議並開發軟件。近年來，李嘉旭教授從事人工胰臟的控製算法研究，並受到美國衛生研究院、能源部的支持對唾液腺的基因網絡進行研究。發表學術論文50余篇，其中被SCI檢索30余篇。
報告時間：2018年6月29日（星期五）下午15:00-16:00
報告地點：必一体育平台二樓會議室
報告摘要：Multi-millions of people suffer diabetes mellitus, including type 1 diabetes and type 2 diabetes, that is caused by the lack of, or relatively insufficient, insulin produced from pancreatic beta-cells. Exogenous insulin or its analogues must be administered in daily base to utilize and lower the chronic high glucose level, ideally, though an artificial pancreas, a medical device consisting of an insulin pump, a glucose monitoring system, and a set of closed loop control (CLC) algorithms. An effective CLC algorithm is still lacking in handling the delayed effects of insulin in delivery mechanisms, GMS and the hepatic glucose production (HGP). The timing discrepancies and dose inaccuracies often cause undesired glucose fluctuations including both hyperglycemia and dangerous hypoglycemia. We aim to formulate an integrated system, consisting of several sub dynamical system models, through which we develop and validate effective CLC algorithms for artificial pancreas with clinical data.
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